Design principles of the proteolytic cascade governing the [sigma.sup.E]-mediated envelope stress response in Escherichia coli: Keys to graded, buffered, and rapid signal transduction
Article Abstract:
The [sigma.sup.E] is seen to mediate an envelope stress response in Escherichia coli and its activity is controlled by regulated degradation of RseA, a membrane-spanning anti-sigma factor. Examination of protease cascade has shown that the initial, signal-sensing cleavage step is rate-limiting and multiple ATP-dependent proteases degrade the cytoplasmic fragment of RseA.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality control
Article Abstract:
The interactions taking place between the human non-protein-coding Y RNAs (nCRNAs) with Ro ribonucleoprotein (RNP) is discussed. The RNP then is found to be extremely useful in the quality control of 5S ribosomal RNA.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
User Contributions:
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